論文雑誌「Chemical Communications」のカバーピクチャーを制作しました［九州大学］
弊社で制作しました九州大学 山田健一先生のカバーアートが
イギリスの王立化学会発行の学術雑誌 Chemical Communications
2021年12月号に選ばれました。
Client
九州大学
大学院薬学研究院 生命物理化学分野
山田健一先生
大学院薬学研究院 生命物理化学分野
山田健一先生
Journal
Chemical Communications
04 January 2022, Issue 1 Link
04 January 2022, Issue 1 Link
Detection and structural analysis of pyrimidine-derived radicals generated on DNA using a profluorescent nitroxide probe
Kosho Yamauchi, Yuta Matsuoka, Masatomo Takahashi, Yoshihiro Izumi, Hideto Naka, Yosuke Taniguchi, Kazuaki Kawai, Takeshi Bamba and Ken-ichi Yamada
The oxidative damage of DNA is associated with aging and the development of various diseases. Although nucleoside-derived radicals play an important role in DNA oxidation, their analysis methods are limited. Herein, we propose a fluorometric detection and structural analysis of radicals on the surface of oxidatively damaged DNA using a profluorescent nitroxide probe combined with liquid chromatography–fluorometry and high-resolution tandem mass spectrometry.
Link
Kosho Yamauchi, Yuta Matsuoka, Masatomo Takahashi, Yoshihiro Izumi, Hideto Naka, Yosuke Taniguchi, Kazuaki Kawai, Takeshi Bamba and Ken-ichi Yamada
The oxidative damage of DNA is associated with aging and the development of various diseases. Although nucleoside-derived radicals play an important role in DNA oxidation, their analysis methods are limited. Herein, we propose a fluorometric detection and structural analysis of radicals on the surface of oxidatively damaged DNA using a profluorescent nitroxide probe combined with liquid chromatography–fluorometry and high-resolution tandem mass spectrometry.
Link
